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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D19
All Species:
44.55
Human Site:
Y387
Identified Species:
81.67
UniProt:
Q8N5T2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5T2
NP_060787.2
526
60268
Y387
Y
H
E
P
S
K
L
Y
Q
I
F
R
E
M
Y
Chimpanzee
Pan troglodytes
XP_001166746
526
60188
Y387
Y
H
E
P
S
K
L
Y
Q
I
F
R
E
M
Y
Rhesus Macaque
Macaca mulatta
XP_001084301
526
60205
Y387
Y
H
E
P
S
K
L
Y
Q
I
F
R
E
M
Y
Dog
Lupus familis
XP_536268
525
59882
Y386
Y
H
E
P
S
K
L
Y
Q
I
F
R
E
M
Y
Cat
Felis silvestris
Mouse
Mus musculus
NP_653100
526
60385
Y387
Y
H
E
P
Y
K
L
Y
Q
I
F
R
E
M
Y
Rat
Rattus norvegicus
NP_001099478
526
60309
Y387
Y
H
E
P
Y
K
L
Y
Q
I
F
R
E
M
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514213
547
62259
Y408
Y
H
E
P
S
K
L
Y
Q
I
F
R
E
M
Y
Chicken
Gallus gallus
XP_420750
526
60176
Y387
Y
H
E
P
S
K
L
Y
Q
I
F
R
E
M
Y
Frog
Xenopus laevis
NP_001089246
527
60151
Y388
Y
H
E
P
S
K
L
Y
Q
V
F
R
E
M
Y
Zebra Danio
Brachydanio rerio
NP_956785
526
60133
Y387
Y
N
E
P
S
K
L
Y
S
V
F
R
E
M
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608913
509
58458
Y372
Y
D
S
P
V
S
L
Y
Y
T
F
R
A
F
Y
Honey Bee
Apis mellifera
XP_623591
536
62028
Y399
Y
D
D
P
C
A
M
Y
Y
T
F
R
A
F
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001191986
401
45886
I271
L
Y
Y
V
F
R
E
I
Y
M
R
H
L
F
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.8
93.3
N.A.
97.3
97.7
N.A.
85.1
91.2
84.6
77.5
N.A.
39.9
43.2
N.A.
47.3
Protein Similarity:
100
100
100
95
N.A.
98.8
99.2
N.A.
89
95.8
93.1
87.2
N.A.
62.3
63
N.A.
61
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
100
93.3
80
N.A.
46.6
40
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
100
100
93.3
N.A.
46.6
53.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
0
0
0
16
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
77
0
0
0
8
0
0
0
0
0
77
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
93
0
0
24
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
70
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
62
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
77
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
0
85
0
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
8
0
0
0
77
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
93
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
8
93
0
0
8
% R
% Ser:
0
0
8
0
62
8
0
0
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% T
% Val:
0
0
0
8
8
0
0
0
0
16
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
93
8
8
0
16
0
0
93
24
0
0
0
0
0
93
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _